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Semaglutide and Tirzepatide for PCOS: Evidence-Based Benefits for Hormones, Insulin Resistance, and Weight
Semaglutide and tirzepatide can significantly improve insulin resistance, hormones, and weight in women with PCOS. Learn what clinical research shows—and whether these medications may be right for you.
Joshua Silva, MD
Nov 23, 20256 min read


Why Weight Loss Is So Hard: A Physician Explains the Biology Behind Weight Loss Resistance
Weight loss is not about willpower—it’s about biology. Learn why your body fights weight loss, why diets fail long-term, and how medical treatments like GLP-1 and GIP medications help you lose weight safely and sustainably.
Joshua Silva, MD
Nov 22, 20256 min read


Zepbound (Tirzepatide) vs. Wegovy (Semaglutide): Which Weight-Loss Medication Is Right for You?
If you’re comparing Zepbound (tirzepatide, GLP-1/GIP) vs. Wegovy (semaglutide, GLP-1) for weight loss, you’re not alone. These two medications are the most effective weight-loss injections available today — and both can help you lose significant weight safely under physician supervision. This guide breaks down how each medication works, how they differ, which one produces more weight loss, what side effects to expect, and how to choose the option that fits your goals, bud
Joshua Silva, MD
Nov 19, 20255 min read


Do I Have to Take Semaglutide or Tirzepatide Forever? — Understanding Long-Term GLP-1 Weight Loss Treatment
Do you have to stay on semaglutide or tirzepatide forever to keep the weight off? Not necessarily—but understanding how these GLP-1 and GLP-1/GIP medications work explains why some people benefit from long-term or maintenance therapy. Potere Health MD, serving St George, Cedar City, and Salt Lake City Utah, offers physician-led, evidence-based guidance to help you maintain lasting results safely and confidently.
Joshua Silva, MD
Nov 14, 20255 min read


GLP-1 & Muscle Loss: Do Semaglutide or Tirzepatide Cause Muscle Wasting?
GLP-1 and GLP-1/GIP medications like semaglutide and tirzepatide don’t cause true muscle wasting. Most weight lost is fat, not muscle. Learn how proper protein intake and resistance training preserve lean mass and support healthy body composition during GLP-1 therapy.
Joshua Silva, MD
Nov 7, 202513 min read


Wegovy® Tablets (Oral Semaglutide) 25 mg: FDA Approval, Dosing, and What to Know
Oral semaglutide (Wegovy® tablets) is now FDA-approved for chronic weight management. This once-daily 25 mg pill uses the same active ingredient as injectable Wegovy®, offering a needle-free option for patients who can’t tolerate injections or prefer a daily tablet. Learn how it works, how it compares to Wegovy® injections, and what this new approval means for access, dosing, and real-world weight-loss results.
Joshua Silva, MD
Oct 30, 20255 min read


Tirzepatide & Testosterone: Understanding the Weight–Hormone Connection
Excess fat lowers testosterone and raises estrogen. This evidence-based article explains how weight loss can restore balance and what studies show about tirzepatide and TRT, including benefits and side effects.
Joshua Silva, MD
Oct 24, 20255 min read


Wegovy (semaglutide) & MASH Approval
Wegovy (semaglutide) is now FDA-approved for MASH with fibrosis (F2–F3) in adults. See what this means for treatment, eligibility, and weight management.
Joshua Silva, MD
Oct 17, 20253 min read


Tirzepatide & Sleep Apnea
Zepbound (tirzepatide) is the first FDA-approved medication for obstructive sleep apnea in adults with obesity. Learn how it works and who may benefit.
Joshua Silva, MD
Oct 10, 20253 min read


ZepBOUND (Tirzepatide) vs Wegovy (Semaglutide)
Wondering if Zepbound or Wegovy is right for you? Learn how they compare for weight loss, safety, and insurance coverage in Utah.
Joshua Silva, MD
Oct 7, 20253 min read


Compounded Semaglutide & Tirzepatide in 2026: FDA Rules, Safety Risks, and How to Choose a Legitimate Pharmacy
Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD As of 2026, compounded semaglutide and tirzepatide are no longer broadly permitted in the United States. Following resolution of nationwide shortages, the FDA ended its temporary enforcement discretion, meaning these medications may now only be compounded under limited, legally defined circumstances .¹–³ On February 21, 2025 , the U.S. Food and Drug Administration formally declared the
Joshua Silva, MD
Oct 3, 20255 min read


Does Semaglutide or Tirzepatide Cause Hair Loss?
Worried about hair loss while taking Wegovy®, Ozempic® (semaglutide), Zepbound®, or Mounjaro® (tirzepatdie)? Learn why shedding happens during weight loss and how to prevent it.
Joshua Silva, MD
Sep 30, 20257 min read


The FDA Green List and compounded GLP-1 Medications Semaglutide & Tirzepatide
Learn how the FDA Green List impacts compounded semaglutide and tirzepatide. Understand Import Alert 66-80, patient safety, and what it does not mean.
Joshua Silva, MD
Sep 26, 20254 min read


Wegovy (Semaglutide) Cardiovascular Risk Reduction
Wegovy (semaglutide) is FDA-approved to reduce major heart risks in adults with obesity/overweight and cardiovascular disease. Learn what it means and who qualifies.
Joshua Silva, MD
Sep 26, 20253 min read
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