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GLP-1 Nutrition & Lifestyle
Protein, hydration, supplements, exercise, and eating strategies that support fat loss, muscle preservation, and fewer side effects.


How to Prevent Muscle Loss on Zepbound® & Ozempic® (GLP-1 Agonists): Evidence-Based Strategies
Worried about muscle loss on Zepbound® or Ozempic®? Discover the specific protein targets and resistance training protocols required to preserve lean mass while taking GLP-1 medications.
Joshua Silva, MD
Apr 25 min read


Do GLP-1 Drugs Like Ozempic and Wegovy Increase Tendon Rupture Risk?
Early research from the 2026 AAOS Annual Meeting indicates that GLP-1 medications like Ozempic and Wegovy may be associated with a higher relative risk of tendon ruptures. However, with an absolute risk increase of less than 1%, most patients remain unaffected. Discover the proposed mechanisms—from rapid activity increases to collagen signaling—and how to mitigate risk while continuing therapy.
Joshua Silva, MD
Mar 174 min read


Ozempic®, Wegovy®, Zepbound® Fatigue: Why Semaglutide and Tirzepatide Can Make You Tired
Feeling tired on Ozempic, Wegovy, or Zepbound? Fatigue is a documented side effect affecting up to 11% of patients. Explore the physiological reasons behind GLP-1 fatigue and learn evidence-based management strategies—like optimizing hydration and protein intake—with Dr. Joshua Silva, MD.
Joshua Silva, MD
Feb 235 min read


Constipation on Tirzepatide or Semaglutide (GLP-1): A Step-by-Step MD Fix
Constipation is a common side effect of GLP-1 medications like semaglutide and tirzepatide. Learn why it happens, how to fix it safely, and when to seek medical care.
Joshua Silva, MD
Jan 315 min read


GLP-1 Nausea: What to Eat (and Avoid) on Wegovy® or Zepbound®
Nausea is one of the most common side effects of GLP-1 medications like Wegovy® and Zepbound®. Learn what foods help, what to avoid, and how simple timing and dosing strategies can improve tolerability.
Joshua Silva, MD
Jan 195 min read


The Best Diet for Semaglutide and Tirzepatide: Evidence-Based Nutrition for GLP-1/GIP Weight Loss
What should you eat while taking semaglutide or tirzepatide? This physician-written guide explains the best evidence-based diet for GLP-1 therapy — including protein, fiber, healthy fats, complex carbs, and sustainable habits that support long-term weight loss.
Joshua Silva, MD
Jan 136 min read


Does Semaglutide or Tirzepatide Cause Hair Loss?
Worried about hair loss while taking Wegovy®, Ozempic® (semaglutide), Zepbound®, or Mounjaro® (tirzepatdie)? Learn why shedding happens during weight loss and how to prevent it.
Joshua Silva, MD
Sep 30, 20257 min read
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