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Side Effects
Common and rare side effects, what’s normal, what’s not, and how to manage nausea, reflux, fatigue, constipation, hair shedding, and more.


Breastfeeding on Ozempic® or Mounjaro®: Is Semaglutide or Tirzepatide Safe?
Is it safe to breastfeed while taking Ozempic® or Mounjaro®? While limited data suggests low transfer into breast milk, official FDA guidance remains cautious due to unknown long-term risks. Learn about the science of peptide transfer, washout periods, and why most clinicians recommend discontinuing GLP-1s during lactation.
Joshua Silva, MD
Feb 94 min read


Diarrhea on GLP-1 Medications (Wegovy®, Zepbound®): Why It Happens and When to Worry
Diarrhea is a common but usually temporary side effect of GLP-1 medications like Wegovy® and Zepbound®. This physician-reviewed guide explains why it happens, food triggers, dose considerations, and when symptoms need medical attention.
Joshua Silva, MD
Feb 48 min read


Constipation on Tirzepatide or Semaglutide (GLP-1): A Step-by-Step MD Fix
Constipation is a common side effect of GLP-1 medications like semaglutide and tirzepatide. Learn why it happens, how to fix it safely, and when to seek medical care.
Joshua Silva, MD
Jan 315 min read


Digestive Enzymes for Ozempic® & Wegovy® Side Effects: Do They Help?
Are sulfur burps and bloating ruining your GLP-1 progress? Many patients turn to digestive enzymes for relief, but the science shows a "mechanism mismatch." Discover why enzymes often fail to fix the "traffic jam" in your stomach—and when they might actually be worth a try.
Joshua Silva, MD
Jan 275 min read


Ozempic® Sulfur Burps, Gas, and Bloating: Why GLP-1 Medications Cause the “Food-Stuck” Feeling
Experiencing sulfur burps or a "stuck" feeling on Ozempic? Dr. Joshua Silva, MD explains the science of delayed gastric emptying and offers 6 actionable tips to reduce gas and bloating.
Joshua Silva, MD
Jan 268 min read


GLP-1 Nausea: What to Eat (and Avoid) on Wegovy® or Zepbound®
Nausea is one of the most common side effects of GLP-1 medications like Wegovy® and Zepbound®. Learn what foods help, what to avoid, and how simple timing and dosing strategies can improve tolerability.
Joshua Silva, MD
Jan 195 min read


GLP-1 & Muscle Loss: Do Semaglutide or Tirzepatide Cause Muscle Wasting?
GLP-1 and GLP-1/GIP medications like semaglutide and tirzepatide don’t cause true muscle wasting. Most weight lost is fat, not muscle. Learn how proper protein intake and resistance training preserve lean mass and support healthy body composition during GLP-1 therapy.
Joshua Silva, MD
Nov 7, 202513 min read


Does Semaglutide or Tirzepatide Cause Hair Loss?
Worried about hair loss while taking Wegovy®, Ozempic® (semaglutide), Zepbound®, or Mounjaro® (tirzepatdie)? Learn why shedding happens during weight loss and how to prevent it.
Joshua Silva, MD
Sep 30, 20257 min read
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