Side Effects

Common and rare side effects, what’s normal, what’s not, and how to manage nausea, reflux, fatigue, constipation, hair shedding, and more.

Infographic explaining constipation on GLP-1 medications such as semaglutide and tirzepatide, showing slowed gastrointestinal motility and evidence-based relief strategies including hydration, soluble fiber (psyllium), physical activity, and osmotic laxatives, with warning signs that require medical attention.

Constipation on Tirzepatide or Semaglutide (GLP-1): A Step-by-Step MD Fix

Constipation is a common side effect of GLP-1 medications like semaglutide and tirzepatide. Learn why it happens, how to fix it safely, and when to seek medical care.

Joshua Silva, MD

2 days ago5 min read

"Medical diagram comparing normal digestion vs delayed gastric emptying on GLP-1s, illustrating why enzymes fail to relieve traffic-jam side effects. Image courtesy of Potere Health MD."

Digestive Enzymes for Ozempic® & Wegovy® Side Effects: Do They Help?

Are sulfur burps and bloating ruining your GLP-1 progress? Many patients turn to digestive enzymes for relief, but the science shows a "mechanism mismatch." Discover why enzymes often fail to fix the "traffic jam" in your stomach—and when they might actually be worth a try.

Joshua Silva, MD

6 days ago5 min read

Medical infographic illustrating how GLP-1 therapy (Ozempic, Wegovy) causes digestive side effects like sulfur burps, gas, bloating, and a "stuck food" feeling by slowing down stomach emptying.

Ozempic® Sulfur Burps, Gas, and Bloating: Why GLP-1 Medications Cause the “Food-Stuck” Feeling

Experiencing sulfur burps or a "stuck" feeling on Ozempic? Dr. Joshua Silva, MD explains the science of delayed gastric emptying and offers 6 actionable tips to reduce gas and bloating.

Joshua Silva, MD

Jan 268 min read

“Foods to eat and avoid for GLP-1 nausea on Wegovy or Zepbound, showing bland low-fat foods versus greasy or sugary meals.”

GLP-1 Nausea: What to Eat (and Avoid) on Wegovy® or Zepbound®

Nausea is one of the most common side effects of GLP-1 medications like Wegovy® and Zepbound®. Learn what foods help, what to avoid, and how simple timing and dosing strategies can improve tolerability.

Joshua Silva, MD

Jan 195 min read

Infographic illustrating healthy body composition changes during GLP-1 and GLP-1/GIP therapy with semaglutide and tirzepatide, showing reduced fat mass and preserved lean muscle through protein intake and resistance training.

GLP-1 & Muscle Loss: Do Semaglutide or Tirzepatide Cause Muscle Wasting?

GLP-1 and GLP-1/GIP medications like semaglutide and tirzepatide don’t cause true muscle wasting. Most weight lost is fat, not muscle. Learn how proper protein intake and resistance training preserve lean mass and support healthy body composition during GLP-1 therapy.

Joshua Silva, MD

Nov 7, 202513 min read

Woman noticing temporary hair shedding during weight loss — not caused by semaglutide or tirzepatide, but due to telogen effluvium.

Does Semaglutide or Tirzepatide Cause Hair Loss?

Worried about hair loss while taking Wegovy®, Ozempic® (semaglutide), Zepbound®, or Mounjaro® (tirzepatdie)? Learn why shedding happens during weight loss and how to prevent it.

Joshua Silva, MD

Sep 30, 20257 min read