Results & Expectations

What real-world weight loss, appetite changes, plateaus, and long-term outcomes look like with semaglutide, tirzepatide, and related therapies.

“Healthy whole foods for an optimal semaglutide (GLP-1) and tirzepatide (GIP) diet, including vegetables, lean protein, healthy fats, whole grains, nuts, seeds, and high-fiber foods.”

The Best Diet for Semaglutide and Tirzepatide: Evidence-Based Nutrition for GLP-1/GIP Weight Loss

What should you eat while taking semaglutide or tirzepatide? This physician-written guide explains the best evidence-based diet for GLP-1 therapy — including protein, fiber, healthy fats, complex carbs, and sustainable habits that support long-term weight loss.

Joshua Silva, MD

Jan 136 min read

“Graph showing a standard weight-loss curve over 18 months, with faster early weight loss followed by gradual slowing and a plateau. Illustrates typical weight-loss physiology used to explain expected results with evidence-based obesity treatments.”

How Fast Will I Lose Weight on Semaglutide or Tirzepatide?

How fast do GLP-1 medications work? This physician-written guide explains what to expect when starting semaglutide or tirzepatide — including early weight-loss patterns, the dose-escalation delay, and real results from clinical trials. Learn why dose matters and how these medications follow a predictable weight-loss curve over 12–18 months.

Joshua Silva, MD

Dec 19, 20254 min read

Medical illustration showing metabolic adaptation after weight loss, comparing before and after silhouettes to explain decreased energy expenditure and increased efficiency that contribute to weight-loss plateaus during semaglutide or tirzepatide treatment.

Why Weight Loss Plateaus on Semaglutide or Tirzepatide — and What to Do About It

Weight loss often slows or plateaus on semaglutide and tirzepatide. Learn why this happens, what clinical trials show, and evidence-based options when progress slows.

Joshua Silva, MD

Dec 16, 20256 min read

Why Weight Loss Is So Hard: A Physician Explains the Biology Behind Weight Loss Resistance

Weight loss is not about willpower—it’s about biology. Learn why your body fights weight loss, why diets fail long-term, and how medical treatments like GLP-1 and GIP medications help you lose weight safely and sustainably.

Joshua Silva, MD

Nov 22, 20256 min read

Person struggling to button jeans, symbolizing weight regain after stopping semaglutide or tirzepatide, used in a Potere Health MD article about long-term GLP-1 weight loss treatment.

Do I Have to Take Semaglutide or Tirzepatide Forever? — Understanding Long-Term GLP-1 Weight Loss Treatment

Do you have to stay on semaglutide or tirzepatide forever to keep the weight off? Not necessarily—but understanding how these GLP-1 and GLP-1/GIP medications work explains why some people benefit from long-term or maintenance therapy. Potere Health MD, serving St George, Cedar City, and Salt Lake City Utah, offers physician-led, evidence-based guidance to help you maintain lasting results safely and confidently.

Joshua Silva, MD

Nov 14, 20255 min read