muscle loss | Potere Health MD

Potere Health MD medical infographic illustrating the "Muscle-Preserving Triad" for patients on GLP-1 agonists like Zepbound and Ozempic. The graphic details resistance training frequency (2-3x weekly), daily protein intake targets (1.2-1.6 g/kg), and the use of DEXA scans or strength monitoring to prevent lean body mass reduction during weight loss.

How to Prevent Muscle Loss on Zepbound® & Ozempic® (GLP-1 Agonists): Evidence-Based Strategies

Worried about muscle loss on Zepbound® or Ozempic®? Discover the specific protein targets and resistance training protocols required to preserve lean mass while taking GLP-1 medications.

Joshua Silva, MD

Apr 25 min read

Infographic illustrating healthy body composition changes during GLP-1 and GLP-1/GIP therapy with semaglutide and tirzepatide, showing reduced fat mass and preserved lean muscle through protein intake and resistance training.

GLP-1 & Muscle Loss: Do Semaglutide or Tirzepatide Cause Muscle Wasting?

GLP-1 and GLP-1/GIP medications like semaglutide and tirzepatide don’t cause true muscle wasting. Most weight lost is fat, not muscle. Learn how proper protein intake and resistance training preserve lean mass and support healthy body composition during GLP-1 therapy.

Joshua Silva, MD

Nov 7, 202513 min read